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Nitric Oxide Effect on Naphthoquinone Toxicity in Endothelial Cells: Role of Bioenergetic Dysfunction and PARP Activation

When produced at physiological levels reactive oxygen species (ROS) can act as signaling molecules to regulate normal vascular function. Produced under pathological conditions, ROS can contribute to oxidative damage of cellular components (e.g., DNA and proteins) and trigger cell death. Moreover, th...

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Main Authors: Broniowska, Katarzyna A., Diers, Anne R., Corbett, John A., Hogg, Neil
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028014/
https://ncbi.nlm.nih.gov/pubmed/23718265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400342t
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