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Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance
In this in vitro study, we determined whether masitinib could reverse multidrug resistance (MDR) in cells overexpressing the ATP binding cassette subfamily G member 2 (ABCG2) transporter. Masitinib (1.25 and 2.5 μM) significantly decreases the resistance to mitoxantrone (MX), SN38 and doxorubicin in...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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D.A. Spandidos
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027943/ https://ncbi.nlm.nih.gov/pubmed/24626598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2341 |
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