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Optimization of GPR40 Agonists for Type 2 Diabetes
[Image: see text] GPR40 (FFA1 and FFAR1) has gained significant interest as a target for the treatment of type 2 diabetes. TAK-875 (1), a GPR40 agonist, lowered hemoglobin A1c (HbA1c) and lowered both postprandial and fasting blood glucose levels in type 2 diabetic patients in phase II clinical tria...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2014
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027784/ https://ncbi.nlm.nih.gov/pubmed/24900872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400501x |
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