Učitavanje...
Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists
[Image: see text] We recently reported the discovery of a potent GPR40 full agonist AM-1638 (1). Herein, we describe our efforts in improving the drug-like properties of the full agonists through the systematic introduction of polar groups in the C-, D-, and A-rings. This led to the discovery of new...
Spremljeno u:
| Glavni autori: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
|
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027632/ https://ncbi.nlm.nih.gov/pubmed/24900845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml4005123 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|