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Identification of a New Scaffold for Hsp90 C-Terminal Inhibition
[Image: see text] Inhibition of Hsp90 C-terminal function is an advantageous therapeutic paradigm for the treatment of cancer. Currently, the majority of Hsp90 C-terminal inhibitors are derived from novobiocin, a natural product traditionally used as an antibiotic. Assisted by molecular docking stud...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027776/ https://ncbi.nlm.nih.gov/pubmed/24900777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400404s |
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