Antitumor Potential of Conjugable Valinomycins Bearing Hydroxyl Sites: In Vitro Studies

[Image: see text] Following our pioneering studies on the direct and efficient introduction of derivatizable hydroxyl handles into the valinomycin (VLM, 1) structure, a K(+)-ionophore with potent antitumor activity, the ensuing conjugable analogues (HyVLMs 2, 3, and 4) have herein been compared to t...

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Main Authors: Iacobazzi, Rosa M., Annese, Cosimo, Azzariti, Amalia, D’Accolti, Lucia, Franco, Massimo, Fusco, Caterina, La Piana, Gianluigi, Laquintana, Valentino, Denora, Nunzio
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2013
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027489/
https://ncbi.nlm.nih.gov/pubmed/24900628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400300q
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