Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

FANCD2 and FANCI function together in the Fanconi anemia network of deoxyribonucleic acid (DNA) crosslink repair. These proteins form the dimeric ID2 complex that binds DNA and becomes monoubiquitinated upon exposure of cells to DNA crosslinking agents. The monoubiquitinated ID2 complex is thought t...

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Bibliographische Detailangaben
Hauptverfasser: Longerich, Simonne, Kwon, Youngho, Tsai, Miaw-Sheue, Hlaing, Aye Su, Kupfer, Gary M., Sung, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027212/
https://ncbi.nlm.nih.gov/pubmed/24623813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku198
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