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Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA
FANCD2 and FANCI function together in the Fanconi anemia network of deoxyribonucleic acid (DNA) crosslink repair. These proteins form the dimeric ID2 complex that binds DNA and becomes monoubiquitinated upon exposure of cells to DNA crosslinking agents. The monoubiquitinated ID2 complex is thought t...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027212/ https://ncbi.nlm.nih.gov/pubmed/24623813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku198 |
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