Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA

FANCD2 and FANCI function together in the Fanconi anemia network of deoxyribonucleic acid (DNA) crosslink repair. These proteins form the dimeric ID2 complex that binds DNA and becomes monoubiquitinated upon exposure of cells to DNA crosslinking agents. The monoubiquitinated ID2 complex is thought t...

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Bibliografiset tiedot
Päätekijät: Longerich, Simonne, Kwon, Youngho, Tsai, Miaw-Sheue, Hlaing, Aye Su, Kupfer, Gary M., Sung, Patrick
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027212/
https://ncbi.nlm.nih.gov/pubmed/24623813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku198
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