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FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL
FANCI is integral to the Fanconi anemia (FA) pathway of DNA damage repair. Upon the occurrence of DNA damage, FANCI becomes monoubiquitinated on Lys-523 and relocalizes to chromatin, where it functions with monoubiquitinated FANCD2 to facilitate DNA repair. We show that FANCI and its C-terminal frag...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749091/ https://ncbi.nlm.nih.gov/pubmed/19589784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.038075 |
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