New Promising Compounds with in Vitro Nanomolar Activity against Trypanosoma cruzi

[Image: see text] The antiparasitic activity of azole and new 4-aminopyridine derivatives has been investigated. The imidazoles 1 and 3–5 showed a potent in vitro antichagasic activity with IC(50) values in the low nanomolar concentration range. The (S)-1, (S)-3, and (S)-5 enantiomers showed (up to)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Friggeri, Laura, Scipione, Luigi, Costi, Roberta, Kaiser, Marcel, Moraca, Francesca, Zamperini, Claudio, Botta, Bruno, Di Santo, Roberto, De Vita, Daniela, Brun, Reto, Tortorella, Silvano
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027138/
https://ncbi.nlm.nih.gov/pubmed/24900706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400039r
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados