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Clicking 3’-azidothymidine into novel potent inhibitors of human immunodeficiency virus
3’-Azidothymidine (AZT) was the first approved antiviral for the treatment of human immunodeficiency virus (HIV). Reported efforts in clicking the 3’-azido group of AZT have not yielded 1,2,3-triazoles active against HIV or any other viruses. We report herein the first AZT-derived 1,2,3-triazoles wi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027054/ https://ncbi.nlm.nih.gov/pubmed/24102161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401232v |
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