Clicking 3’-azidothymidine into novel potent inhibitors of human immunodeficiency virus

3’-Azidothymidine (AZT) was the first approved antiviral for the treatment of human immunodeficiency virus (HIV). Reported efforts in clicking the 3’-azido group of AZT have not yielded 1,2,3-triazoles active against HIV or any other viruses. We report herein the first AZT-derived 1,2,3-triazoles wi...

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Hlavní autoři: Sirivolu, Venkata Ramana, Vernekar, Sanjeev Kumar V., Ilina, Tatiana, Myshakina, Nataliya S., Parniak, Michael A., Wang, Zhengqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027054/
https://ncbi.nlm.nih.gov/pubmed/24102161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401232v
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