Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis

Mutations in hemojuvelin (HJV) are the most common cause of the juvenile-onset form of the iron overload disorder hereditary hemochromatosis. The discovery that HJV functions as a co-receptor for the bone morphogenetic protein (BMP) family of signaling molecules helped to identify this signaling pat...

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Bibliographic Details
Main Authors: Core, Amanda B., Canali, Susanna, Babitt, Jodie L.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026703/
https://ncbi.nlm.nih.gov/pubmed/24860505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00104
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