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Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway

Caffeine is a naturally occurring methylxanthine that acts as a non-selective adenosine receptor antagonist. Epidemiological studies demonstrated habitual coffee drinking to be significantly associated with liver cancer survival. We aimed to investigate the effects of caffeine and its analog CGS 159...

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Main Authors: Edling, Charlotte E, Selvaggi, Federico, Ghonaim, Ragheda, Maffucci, Tania, Falasca, Marco
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026075/
https://ncbi.nlm.nih.gov/pubmed/24521981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28018
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