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Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway

Caffeine is a naturally occurring methylxanthine that acts as a non-selective adenosine receptor antagonist. Epidemiological studies demonstrated habitual coffee drinking to be significantly associated with liver cancer survival. We aimed to investigate the effects of caffeine and its analog CGS 159...

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Bibliografiske detaljer
Main Authors: Edling, Charlotte E, Selvaggi, Federico, Ghonaim, Ragheda, Maffucci, Tania, Falasca, Marco
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026075/
https://ncbi.nlm.nih.gov/pubmed/24521981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28018
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