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Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer
BACKGROUND: The very aggressive nature and low survival rate of pancreatic ductal adenocarcinoma (PDAC) dictates the necessity to find novel efficacious therapies. Recent evidence suggests that phosphoinositide 3-kinase (PI3K) and 3-phosphoinositide-dependent protein kinase 1 (PDK1) are key effector...
में बचाया:
| में प्रकाशित: | J Exp Clin Cancer Res |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6518649/ https://ncbi.nlm.nih.gov/pubmed/31088502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1191-2 |
| टैग : |
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