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Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth

Objective: Neuroblastoma is a common neuroendocrine (NE) tumor that presents in early childhood, with a high incidence of malignancy and recurrence. The glycogen synthase kinase-3 (GSK-3) pathway is a potential therapeutic target, as this pathway has been shown to be crucial in the management of oth...

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Bibliografiske detaljer
Main Authors: Carter, Yvette M, Kunnimalaiyaan, Selvi, Chen, Herbert, Gamblin, T Clark, Kunnimalaiyaan, Muthusamy
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026073/
https://ncbi.nlm.nih.gov/pubmed/24521712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28015
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