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TRP53 activates a global autophagy program to promote tumor suppression
The mechanisms by which the TP53/TRP53 transcription factor acts as a tumor suppressor remain incompletely understood. To gain new insights into TP53/TRP53 biology, we used ChIP-seq and RNA-seq technologies to define global TRP53 transcriptional networks in primary cells subjected to DNA damage. Int...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026029/ https://ncbi.nlm.nih.gov/pubmed/23899499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.25833 |
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