UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

The proper trafficking and localization of Toll-like receptors (TLRs) are important for specific ligand recognition and efficient signal transduction. The TLRs sensing bacterial membrane components are expressed on the cell surface and recruit signaling adaptors to the plasma membrane upon stimulati...

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Hlavní autoři: Huh, Ji-Won, Shibata, Takuma, Hwang, Misun, Kwon, Eun-Hye, Jang, Min Seong, Fukui, Ryutaro, Kanno, Atsuo, Jung, Da-Jung, Jang, Myoung Ho, Miyake, Kensuke, Kim, You-Me
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024908/
https://ncbi.nlm.nih.gov/pubmed/24778236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322838111
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