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UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

The proper trafficking and localization of Toll-like receptors (TLRs) are important for specific ligand recognition and efficient signal transduction. The TLRs sensing bacterial membrane components are expressed on the cell surface and recruit signaling adaptors to the plasma membrane upon stimulati...

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Autors principals: Huh, Ji-Won, Shibata, Takuma, Hwang, Misun, Kwon, Eun-Hye, Jang, Min Seong, Fukui, Ryutaro, Kanno, Atsuo, Jung, Da-Jung, Jang, Myoung Ho, Miyake, Kensuke, Kim, You-Me
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024908/
https://ncbi.nlm.nih.gov/pubmed/24778236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322838111
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