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Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development

Folliculin-interacting protein 1 (Fnip1) is an adaptor protein that physically interacts with AMPK, an energy-sensing kinase that stimulates mitochondrial biogenesis and autophagy in response to low ATP, while turning off energy consumption mediated by mammalian target of rapamycin. Previous studies...

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Detalhes bibliográficos
Main Authors: Park, Heon, Tsang, Mark, Iritani, Brian M., Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024901/
https://ncbi.nlm.nih.gov/pubmed/24785297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406473111
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