Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.

gp130 is a ubiquitously expressed signal-transducing receptor component shared by interleukin 6, interleukin 11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and cardiotrophin 1. To investigate physiological roles of gp130 and to examine pathological consequences of a lack...

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Hlavní autoři: Yoshida, K, Taga, T, Saito, M, Suematsu, S, Kumanogoh, A, Tanaka, T, Fujiwara, H, Hirata, M, Yamagami, T, Nakahata, T, Hirabayashi, T, Yoneda, Y, Tanaka, K, Wang, W Z, Mori, C, Shiota, K, Yoshida, N, Kishimoto, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC40247/
https://ncbi.nlm.nih.gov/pubmed/8552649
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