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FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression

PURPOSE: The transcription factor Forkhead box M1 (FOXM1) plays critical roles in cancer development and progression. However, the regulatory role and underlying mechanisms of FOXM1 in cancer metabolism are unknown. In this study, we characterized the regulation of aerobic glycolysis by FOXM1 and it...

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Bibliografiske detaljer
Main Authors: Cui, Jiujie, Shi, Min, Xie, Dacheng, Wei, Daoyan, Jia, Zhiliang, Zheng, Shaojiang, Gao, Yong, Huang, Suyun, Xie, Keping
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4024335/
https://ncbi.nlm.nih.gov/pubmed/24634381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2407
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