ROBUST PHOTO-REGULATION OF GABA(A) RECEPTORS BY ALLOSTERIC MODULATION WITH A PROPOFOL ANALOG

Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photo-regulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a GABA(A)R allosteric modulator, that we have modi...

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Detalhes bibliográficos
Main Authors: Yue, Lan, Pawlowski, Michal, Dellal, Shlomo S., Xie, An, Feng, Feng, Otis, Thomas S., Bruzik, Karol S., Qian, Haohua, Pepperberg, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023869/
https://ncbi.nlm.nih.gov/pubmed/23033071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2094
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