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Improved in Vitro Efficacy of Gold Nanoconstructs by Increased Loading of G-quadruplex Aptamer

[Image: see text] This paper describes how in vitro efficacy of aptamer-loaded gold nanostars (Apt-AuNS) can be enhanced by the increased loading of a G-quadruplex homodimer AS1411 (Apt) on the AuNS surface. In a low pH buffer environment, the loading density of Apt on AuNS was increased up to 2.5 t...

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Autors principals: Dam, Duncan Hieu M., Lee, Raymond C., Odom, Teri W.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023846/
https://ncbi.nlm.nih.gov/pubmed/24689438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl500844m
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