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Enhanced HER2 Degradation in Breast Cancer Cells by Lysosome-Targeting Gold Nanoconstructs

This paper describes how gold nanoparticle nanoconstructs can enhance anti-cancer effects of lysosomal targeting aptamers in breast cancer cells. Nanoconstructs consisting of anti-HER2 aptamer (human epidermal growth factor receptor 2, HApt) densely grafted on gold nanostars (AuNS) first targeted HE...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Lee, Hyojin, Dam, Duncan Hieu M., Ha, Ji Won, Yue, Jun, Odom, Teri W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279887/
https://ncbi.nlm.nih.gov/pubmed/26335372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.5b05138
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