Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

Persister cells represent a multidrug-tolerant (MDT), physiologically distinct subpopulation of bacteria. The ability of these organisms to survive lethal antibiotic doses raises concern over their potential role in chronic disease, such as recurrent urinary tract infection (RUTI). Persistence is be...

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Библиографические подробности
Главные авторы: Goneau, Lee W., Yeoh, Nigel S., MacDonald, Kyle W., Cadieux, Peter A., Burton, Jeremy P., Razvi, Hassan, Reid, Gregor
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Susceptibility
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023725/
https://ncbi.nlm.nih.gov/pubmed/24449771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02552-13
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