Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

Persister cells represent a multidrug-tolerant (MDT), physiologically distinct subpopulation of bacteria. The ability of these organisms to survive lethal antibiotic doses raises concern over their potential role in chronic disease, such as recurrent urinary tract infection (RUTI). Persistence is be...

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Détails bibliographiques
Auteurs principaux: Goneau, Lee W., Yeoh, Nigel S., MacDonald, Kyle W., Cadieux, Peter A., Burton, Jeremy P., Razvi, Hassan, Reid, Gregor
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Susceptibility
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023725/
https://ncbi.nlm.nih.gov/pubmed/24449771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02552-13
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