Antifolate Agents Against Wild and Mutant Strains of Plasmodium falciparum

Plasmodium falciparum dihydrofolate reductase is an important target for antimalarial chemotherapy. The emergence of resistance has significantly reduced the efficacy of the classic antifolate drugs cycloguanil and pyrimethamine. In this paper we report new dihydrofolate reductase inhibitors identif...

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Détails bibliographiques
Auteurs principaux: Shaikh, M. S., Rana, J., Gaikwad, D., Leartsakulpanich, U., Ambre, Premlata K., Pissurlenkar, R. R. S., Coutinho, E. C.
Format: Artigo
Langue:Inglês
Publié: Medknow Publications & Media Pvt Ltd 2014
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023280/
https://ncbi.nlm.nih.gov/pubmed/24843184
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