Submicroscopic Gametocytes and the Transmission of Antifolate-Resistant Plasmodium falciparum in Western Kenya

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the dhfr and dhps genes are associated with sulphadoxine-pyrimethamine (SP) treatment failure and gametocyte carriage. This may result in enhanced transmission of mutant malaria parasites, as previously shown for chloroquine resistant parasites....

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Main Authors: Oesterholt, Mayke J. A. M., Alifrangis, Michael, Sutherland, Colin J., Omar, Sabah A., Sawa, Patrick, Howitt, Christina, Gouagna, Louis C., Sauerwein, Robert W., Bousema, Teun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632751/
https://ncbi.nlm.nih.gov/pubmed/19194499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004364
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