Primaquine Clears Submicroscopic Plasmodium falciparum Gametocytes that Persist after Treatment with Sulphadoxine-Pyrimethamine and Artesunate

BACKGROUND: P. falciparum gametocytes may persist after treatment with sulphadoxine-pyrimethamine (SP) plus artesunate (AS) and contribute considerably to malaria transmission. We determined the efficacy of SP+AS plus a single dose of primaquine (PQ, 0.75 mg/kg) on clearing gametocytaemia measured b...

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Hauptverfasser: Shekalaghe, Seif, Drakeley, Chris, Gosling, Roly, Ndaro, Arnold, van Meegeren, Monique, Enevold, Anders, Alifrangis, Michael, Mosha, Frank, Sauerwein, Robert, Bousema, Teun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995753/
https://ncbi.nlm.nih.gov/pubmed/17925871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001023
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