Common genetic variants do not associate with CAD in familial hypercholesterolemia

In recent years, multiple loci dispersed on the genome have been shown to be associated with coronary artery disease (CAD). We investigated whether these common genetic variants also hold value for CAD prediction in a large cohort of patients with familial hypercholesterolemia (FH). We genotyped a t...

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Autori principali: van Iperen, Erik P A, Sivapalaratnam, Suthesh, Boekholdt, S Matthijs, Hovingh, G Kees, Maiwald, Stephanie, Tanck, Michael W, Soranzo, Nicole, Stephens, Jonathan C, Sambrook, Jennifer G, Levi, Marcel, Ouwehand, Willem H, Kastelein, John JP, Trip, Mieke D, Zwinderman, Aeilko H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023217/
https://ncbi.nlm.nih.gov/pubmed/24219970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.242
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