Common genetic variants do not associate with CAD in familial hypercholesterolemia

In recent years, multiple loci dispersed on the genome have been shown to be associated with coronary artery disease (CAD). We investigated whether these common genetic variants also hold value for CAD prediction in a large cohort of patients with familial hypercholesterolemia (FH). We genotyped a t...

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Detalhes bibliográficos
Main Authors: van Iperen, Erik P A, Sivapalaratnam, Suthesh, Boekholdt, S Matthijs, Hovingh, G Kees, Maiwald, Stephanie, Tanck, Michael W, Soranzo, Nicole, Stephens, Jonathan C, Sambrook, Jennifer G, Levi, Marcel, Ouwehand, Willem H, Kastelein, John JP, Trip, Mieke D, Zwinderman, Aeilko H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023217/
https://ncbi.nlm.nih.gov/pubmed/24219970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.242
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