Common genetic variants do not associate with CAD in familial hypercholesterolemia

In recent years, multiple loci dispersed on the genome have been shown to be associated with coronary artery disease (CAD). We investigated whether these common genetic variants also hold value for CAD prediction in a large cohort of patients with familial hypercholesterolemia (FH). We genotyped a t...

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Auteurs principaux: van Iperen, Erik P A, Sivapalaratnam, Suthesh, Boekholdt, S Matthijs, Hovingh, G Kees, Maiwald, Stephanie, Tanck, Michael W, Soranzo, Nicole, Stephens, Jonathan C, Sambrook, Jennifer G, Levi, Marcel, Ouwehand, Willem H, Kastelein, John JP, Trip, Mieke D, Zwinderman, Aeilko H
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023217/
https://ncbi.nlm.nih.gov/pubmed/24219970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.242
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