A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis

Cardiovascular disease (CVD) is a major cause of death in Western societies. CVD risk is largely genetically determined. The molecular pathology is, however, not elucidated in a large number of families suffering from CVD. We applied exclusion linkage analysis and next-generation sequencing to eluci...

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Bibliographic Details
Published in:Eur J Hum Genet
Main Authors: Maiwald, Stephanie, Motazacker, Mahdi M, van Capelleveen, Julian C, Sivapalaratnam, Suthesh, van der Wal, Allard C, van der Loos, Chris, Kastelein, John J P, Ouwehand, Willem H, Hovingh, G Kees, Trip, Mieke D, van Buul, Jaap D, Dallinga-Thie, Geesje M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795224/
https://ncbi.nlm.nih.gov/pubmed/25898923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.70
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