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Heterologous Src Homology 4 Domains Support Membrane Anchoring and Biological Activity of HIV-1 Nef
The HIV-1 pathogenicity factor Nef enhances viral replication by modulation of multiple host cell transport and signaling pathways. Nef associates with membranes via an N-terminal Src homology 4 (SH4) domain, and membrane association is believed to be essential for its biological functions. At which...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4022873/ https://ncbi.nlm.nih.gov/pubmed/24706755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563528 |
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