Erroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics

BACKGROUND: The revolution in cancer genomics shows that the dominant mutations are CG->TA transitions. The sources of these mutations are probably two host cell cytidine deaminases APOBEC3A and APOBEC3B. The former in particular can access nuclear DNA and monotonously introduce phenomenal number...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Suspène, R, Caval, V, Henry, M, Bouzidi, M S, Wain-Hobson, S, Vartanian, J-P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Genetics and Genomics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021520/
https://ncbi.nlm.nih.gov/pubmed/24691422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.176
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