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Erroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics
BACKGROUND: The revolution in cancer genomics shows that the dominant mutations are CG->TA transitions. The sources of these mutations are probably two host cell cytidine deaminases APOBEC3A and APOBEC3B. The former in particular can access nuclear DNA and monotonously introduce phenomenal number...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4021520/ https://ncbi.nlm.nih.gov/pubmed/24691422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.176 |
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