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Beneficial Effects of RAF Inhibitor in Mutant BRAF Splice Variant-expressing Melanoma
Resistance to RAF inhibitors such as vemurafenib and dabrafenib is a major clinical problem in the treatment of melanoma. Mutant BRAF melanoma patients that progress on RAF inhibitors have limited treatment options and drug removal from resistant tumors may elicit multiple effects. A frequent mechan...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020954/ https://ncbi.nlm.nih.gov/pubmed/24520098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0581 |
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