Mouse and Human BAC Transgenes Recapitulate Tissue-Specific Expression of the Vitamin D Receptor in Mice and Rescue the VDR-Null Phenotype

The biological actions of 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) are mediated by the vitamin D receptor (VDR), which is expressed in numerous target tissues in a cell type-selective manner. Recent studies using genomic analyses and recombineered bacterial artificial chromosomes (BACs) have def...

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Hlavní autoři: Lee, Seong Min, Bishop, Kathleen A., Goellner, Joseph J., O'Brien, Charles A., Pike, J. Wesley
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
Calcium-Regulating Hormones
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020932/
https://ncbi.nlm.nih.gov/pubmed/24693968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1107
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