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Stable expression of human VDR in murine VDR-null cells recapitulates vitamin D mediated anti-cancer signaling.

Mammary tumor cells derived from vitamin D receptor (VDR) knock-out (KO) mice were engineered to stably express wild-type or mutated VDR for characterization of the mechanisms by which 1,25-dihydroxyvitamin D (1,25D), the VDR ligand, mediates growth regulation. Although KO cells were completely resi...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Keith, Meggan E., LaPorta, Erika, Welsh, JoEllen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743320/
https://ncbi.nlm.nih.gov/pubmed/23681781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21975
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