Side-Chain Oxysterols Modulate Cholesterol Accessibility through Membrane Remodeling

[Image: see text] Side-chain oxysterols, such as 25-hydroxycholesterol (25-HC), are key regulators of cholesterol homeostasis. New evidence suggests that the alteration of membrane structure by 25-HC contributes to its regulatory effects. We have examined the role of oxysterol membrane effects on ch...

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Main Authors: Bielska, Agata A., Olsen, Brett N., Gale, Sarah E., Mydock-McGrane, Laurel, Krishnan, Kathiresan, Baker, Nathan A., Schlesinger, Paul H., Covey, Douglas F., Ory, Daniel S.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020583/
https://ncbi.nlm.nih.gov/pubmed/24758724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5000096
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