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Exploration of sequence space as the basis of viral RNA genome segmentation
The mechanisms of viral RNA genome segmentation are unknown. On extensive passage of foot-and-mouth disease virus in baby hamster kidney-21 cells, the virus accumulated multiple point mutations and underwent a transition akin to genome segmentation. The standard single RNA genome molecule was replac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020086/ https://ncbi.nlm.nih.gov/pubmed/24757055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323136111 |
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