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Emergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate

In the past decade, ubiquitination has been well documented to have multifaceted roles in regulating NF-κB activation in mammals. However, its function, especially how deubiquitinating enzymes balance the NF-κB activation, remains largely elusive in invertebrates. Investigating bbtA20 and its bindin...

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Detalhes bibliográficos
Main Authors: Yuan, Shaochun, Dong, Xiangru, Tao, Xin, Xu, Liqun, Ruan, Jie, Peng, Jian, Xu, Anlong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020044/
https://ncbi.nlm.nih.gov/pubmed/24753567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321187111
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