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PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

Double-stranded RNA-dependent protein kinase (PKR) regulates antiviral activity, immune responses, apoptosis and neurotoxicity. Gliatropic coronavirus infection induced PKR activation in infected as well uninfected cells within the central nervous system (CNS). However, PKR deficiency only modestly...

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Podrobná bibliografie
Hlavní autoři: Kapil, Parul, Stohlman, Stephen A., Hinton, David R., Bergmann, Cornelia C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier B.V. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019976/
https://ncbi.nlm.nih.gov/pubmed/24642385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.02.012
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