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PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis
Double-stranded RNA-dependent protein kinase (PKR) regulates antiviral activity, immune responses, apoptosis and neurotoxicity. Gliatropic coronavirus infection induced PKR activation in infected as well uninfected cells within the central nervous system (CNS). However, PKR deficiency only modestly...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier B.V.
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019976/ https://ncbi.nlm.nih.gov/pubmed/24642385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.02.012 |
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