PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis

Double-stranded RNA-dependent protein kinase (PKR) regulates antiviral activity, immune responses, apoptosis and neurotoxicity. Gliatropic coronavirus infection induced PKR activation in infected as well uninfected cells within the central nervous system (CNS). However, PKR deficiency only modestly...

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Bibliografische gegevens
Hoofdauteurs: Kapil, Parul, Stohlman, Stephen A., Hinton, David R., Bergmann, Cornelia C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier B.V. 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019976/
https://ncbi.nlm.nih.gov/pubmed/24642385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.02.012
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