Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans

C. elegans is extensively used to study the Wnt-pathway and most of the core-signalling components are known. Four β-catenins are important gene expression regulators in Wnt-signalling. One of these, bar-1, is part of the canonical Wnt-pathway. Together with Wnt effector pop-1, bar-1 forms a transcr...

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Autori principali: van der Bent, M. Leontien, Sterken, Mark G., Volkers, Rita J. M., Riksen, Joost A. G., Schmid, Tobias, Hajnal, Alex, Kammenga, Jan E., Snoek, L. Basten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019968/
https://ncbi.nlm.nih.gov/pubmed/24819947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04926
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