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Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans
C. elegans is extensively used to study the Wnt-pathway and most of the core-signalling components are known. Four β-catenins are important gene expression regulators in Wnt-signalling. One of these, bar-1, is part of the canonical Wnt-pathway. Together with Wnt effector pop-1, bar-1 forms a transcr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019968/ https://ncbi.nlm.nih.gov/pubmed/24819947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04926 |
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