Combining affinity proteomics and network context to identify new phosphatase substrates and adapters in growth pathways

Protein phosphorylation homoeostasis is tightly controlled and pathological conditions are caused by subtle alterations of the cell phosphorylation profile. Altered levels of kinase activities have already been associated to specific diseases. Less is known about the impact of phosphatases, the enzy...

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Detalhes bibliográficos
Main Authors: Sacco, Francesca, Boldt, Karsten, Calderone, Alberto, Panni, Simona, Paoluzi, Serena, Castagnoli, Luisa, Ueffing, Marius, Cesareni, Gianni
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019850/
https://ncbi.nlm.nih.gov/pubmed/24847354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00115
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